Macrophage Colony-Stimulating Factor

A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF is a disulfide-bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor (RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR).

Also Known As:

Colony Stimulating Factor 1; Colony Stimulating Factor, Macrophage; CSF-1; CSF-M; Colony-Stimulating Factor 1; Colony-Stimulating Factor, Macrophage; M-CSF

Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - Colony-Stimulating Factors: 1599
      - Macrophage Colony-Stimulating Factor: 2319
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - Hematopoietic Cell Growth Factors: 13
        Colony-Stimulating Factors: 1599
        Macrophage Colony-Stimulating Factor: 2319
  - Glycoproteins: 24834
    - Colony-Stimulating Factors: 1599
      - Macrophage Colony-Stimulating Factor: 2319
- Peptides: 82426
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - Hematopoietic Cell Growth Factors: 13
        Colony-Stimulating Factors: 1599
        Macrophage Colony-Stimulating Factor: 2319
Biological Factors: 2472
- Intercellular Signaling Peptides and Proteins: 29768
  - Cytokines: 164289
    - Hematopoietic Cell Growth Factors: 13
      - Colony-Stimulating Factors: 1599
        Macrophage Colony-Stimulating Factor: 2319

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Disease

Drug/Important Bio-Agent (IBA)